Time-Space Research Laboratory

The Chronos Institute, also known as the Time-Space Research Laboratory (時空研究所), is a facility that researches space and time.

Mega Man II
An experimental time machine is stolen from the Chronos Institute by Dr. Wily, who uses it to bring a a future version of Mega Man to fight himself in the present. Dr. Light learns of Dr. Wily's plot through Rush's enhanced sense of smell, and immediately sends Mega Man to search for Dr. Wily.

Mega Man (Archie Comics)
The Chronos Institute appeared briefly in issue 20, where Dr. Wily modifies it into a base. During the crossover Worlds Collide, the Chronos Institute is mentioned by Dr. Light in Sonic the Hedgehog Issue 248. Time Man works in the institute.

Rockman World 2
Dr. Light, Mega Man, and Rush analyze the Time-Space Research Laboratory, which had a time machine stolen. Using his nose, Rush discovers Dr. Wily is behind the theft, and Crash Man appears to make sure Mega Man will not disturb Dr. Wily. After Crash Man's defeat, Metal Man, Air Man, and Wood Man appear and attack Mega Man, but they are also defeated. After the battle, Mega Man leaves the laboratory to search Dr. Wily.

Trivia

 * The name "Chronos Institute" is coined by the English Mega Man II manual. It is called "Time-Space Research Laboratory" in Mega Man Official Complete Works.