Insanity

Insanity is a recurring theme is the Mega Man franchise. Many characters in the series exhibit symptoms of mania or outright insanity, often seeking to cause great harm or destruction to others or the world in the name of their cause. Though these causes are often meant to do good for either humanity or Reploids, the amount of damage it will inflict heavily outweighs the positive changes, and must be stopped. Some individuals, however, seek revenge for something that happened to them or for someone they have lost.

Original Mega Man series
Dr. Wily.

Grenade Man.

Burner Man.

Mega Man X series
Sigma.

Vile.

Double.

Gate.

Lumine.

Certain Mavericks.

Mega Man Zero series
Dr. Weil.

Omega.

Mega Man Battle Network series
Lord Wily.

Sean Obihiro.

Speedy Dave.

Anetta.

Dr. Regal.

Mega Man Star Force series
Dr. Vega.

Mega Man cartoon series
Dr. Wily (Ruby-Spears).

MegaMan NT Warrior series
Mr. Wily.

Dr. Regal (anime).

Darkloids.

Domon Atsuki.

Professor (anime).

Mega Man Megamix and Gigamix
Bass (Mega Man Megamix).